Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus
| Avignon (Le Pontet) | Brussels Airport BRU (Parking P14) | Cheapest | ||||
 | Bus | Avignon (Le Pontet) | Brussels-South (Gare du Midi) | Fastest | ||||
| Bus | Avignon (Le Pontet) | Brussels-South (Gare du Midi) | No tags | ||||
| Bus
| Avignon (Le Pontet) | Brussels North Train Station | No tags | ||||
| Bus | Avignon (Le Pontet) | Brussels North Train Station | No tags | ||||
| Bus
| Avignon (Le Pontet) | Brussels North Train Station | No tags | ||||
| Bus | Avignon (Le Pontet) | Brussels North Train Station | No tags | ||||
| Bus
| Avignon (Le Pontet) | Brussels North Train Station | No tags |
Last refresh of the prices: Today at 3:11 AM CEST.
Get from Avignon to Brussels
The journey takes about 15 hours 30 minutes, and with fares starting at just $52, it presents an excellent value for a comfortable ride.
Bus stations and stops in Avignon and Brussels
Stops in Avignon
- A
Gare Routière Avignon
54 Boulevard Saint-Roch, 84000 Avignon, France - B
Parking St. Bénézet
Boulevard du Rhône, 84000 Avignon, France - C
Avignon (TGV-Station)
Place de l'Europe, 84000 Avignon, France - D
Avignon (Bus Station)
42 Boulevard Saint-Roch, 84000 Avignon, France
Stops in Brussels
- A
Brussels South (Gare du Midi)
Rue de France 85, 1060 Saint-Gilles, Belgium - B
Brux-Nord
Boulevard Simon Bolivar 7, 1030 Schaerbeek, Belgium - C
Centrale
Rue de Loxum 5, 1000 Bruxelles, Belgium - D
Congrès
Pachecolaan 5, 1000 Brussel, Belgium
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Frequently asked questions about travelling from Avignon to Brussels by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Avignon to Brussels?
The cheapest bus tickets from Avignon to Brussels start from $52. The average price for this route is around $97. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Avignon to Brussels?
The average bus travel time from Avignon to Brussels is 15h 30m, covering a distance of 768 km. The quickest bus can get you there in 13h 10m and is operated by BlaBlaCar Bus.
Which bus companies service the Avignon to Brussels route?
Several major bus companies operate on this route with 5 buses available per day, including services from FlixBus, BlaBlaCar Bus.
What are the earliest and latest departure times for the bus from Avignon to Brussels?
The earliest bus departs from Avignon to Brussels at 12:15am. And the latest bus departs at 11:45pm.
What are the CO₂ emissions for the bus trip from Avignon to Brussels?
A bus trip from Avignon to Brussels generates an estimated 19.1812 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Avignon to Brussels?
According to Busbud customers, the highest-rated bus company on this route is BlaBlaCar Bus, with an average rating of 3.7 out of 5 stars based on 12926 reviews.
Which bus company has the best Wi-Fi from Avignon to Brussels?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Avignon to Brussels?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Avignon to Brussels?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is BlaBlaCar Bus, with a cleanliness rating of 4.3 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Avignon to Brussels was searched and found on Oct 20, 2026 with a price of $79To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Avignon to Brussels, as early as possible.
You can expect to pay from $79 to $219 for a bus ticket from Avignon to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at $79 which is on 2026-10-20.
What's the cheapest way to go from Avignon to Brussels?
The Bus is the cheapest travel choice for this destination
