Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Rome Tiburtina Bus Station | Lyon Avenue Tony Garnier | Cheapest | ||||
| Bus | Rome Tiburtina Bus Station | Lyon Avenue Tony Garnier | Fastest | ||||
 | Bus | Rome Tiburtina Bus Station | Lyon - Gerland Bus Station | No tags | ||||
 | Bus | Rome Tiburtina Bus Station | Gare routière de Gerland | No tags | ||||
| Bus | Rome Tiburtina Bus Station | Lyon Avenue Tony Garnier | No tags | ||||
| Bus | Rome Tiburtina Bus Station | Gare routière de Gerland | No tags | ||||
| Bus | Rome Tiburtina Bus Station | Lyon Avenue Tony Garnier | No tags | ||||
| Bus | Rome Tiburtina Bus Station | Aéroport LYS | No tags |
Last refresh of the prices: Yesterday at 2:31 PM CEST.
Compare 2 ways to go from Rome to Lyon
Among the sustainable travel choices, the Bus stands out as a good way to reach Lyon. The journey takes about 16 hours 35 minutes, and with fares starting at just THB 1,230, it presents an excellent value for a comfortable ride.
Bus stations and stops in Rome and Lyon
Stops in Rome
- A
Rome Tiburtina Bus Station
Largo Guido Mazzoni, 3, 00162 Roma, Italy - D
Castro Pretorio
Viale Castro Pretorio 76, 00185 Roma, Italy - E
Roma
- F
Anagnina
Via Vincenzo Giudice, 00173 Roma RM, Italy
Stops in Lyon
- B
Perrache
Rue de Esplanade, 69002 Lyon, France - C
Lyon
8 Rue de la Paix, 69700 Givors, France - D
Quai de Saoune
4 Cours de Verdun Rambaud, 69002 Lyon, France - E
Villeurbanne INSA
20 Avenue Albert Einstein, 69100 Villeurbanne, France - F
Les Charrières
Les Charrières, 69570 Dardilly, France
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Frequently asked questions about travelling from Rome to Lyon by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Rome to Lyon?
The cheapest bus tickets from Rome to Lyon start from THB 1,230. The average price for this route is around THB 3,496. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Rome to Lyon?
The average bus travel time from Rome to Lyon is 16h 35m, covering a distance of 744 km. The quickest bus can get you there in 14h 30m and is operated by Itabus.
Which bus companies service the Rome to Lyon route?
Several major bus companies operate on this route with 24 buses available per day, including services from FlixBus, Itabus, BlaBlaCar Bus, RegioJet.
What are the earliest and latest departure times for the bus from Rome to Lyon?
The earliest bus departs from Rome to Lyon at 12:10am. And the latest bus departs at 11:50pm.
What are the CO₂ emissions for the bus trip from Rome to Lyon?
A bus trip from Rome to Lyon generates an estimated 18.592975000000003 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Rome to Lyon?
According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1102 reviews.
Which bus company has the best Wi-Fi from Rome to Lyon?
Based on Busbud reviews, the bus company RegioJet has the highest Wi-Fi rating with a score of 3.8.
Which bus company has the best on-time performance from Rome to Lyon?
According to Busbud traveller reviews, the most punctual bus company on this route is RegioJet, with a punctuality rating of 4.1 out of 5 stars.
Which bus company has the cleanest buses from Rome to Lyon?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.4 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Rome to Lyon was searched and found on Aug 6, 2026 with a price of THB 1,605To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rome to Lyon, as early as possible.
You can expect to pay from THB 1,605 to THB 7,863 for a bus ticket from Rome to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at THB 1,725 which is on 2026-08-07.
Usually Itabus, FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
