Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Rome Tiburtina Bus Station | Terminal Interbus | No tags | ||||
| Bus | Rome Tiburtina Bus Station | Terminal Interbus | No tags | ||||
| Bus | Rome Tiburtina Bus Station | Terminal Interbus | No tags | ||||
| Bus | Rome Tiburtina Bus Station | Terminal Interbus | No tags | ||||
| Bus | Rome Tiburtina Bus Station | Terminal Interbus | No tags |
Compare 2 ways to travel from Rome to Syracuse
Among the sustainable travel choices, the Train stands out as a good way to reach Syracuse. The journey takes about 11 hours 5 minutes and with fares starting at just R$296, it presents an excellent value for a comfortable ride.
Where are the popular stops in Rome and Syracuse?
Stops in Rome
- APiazza dei Cinquecento 1, 00185 Roma RM, Italy
- BLargo Guido Mazzoni, 3, 00162 Roma, Italy
- C
Rome Fiumicino Airport (FCO), Train station
Fiumicino Aeroporto, 00054 Fiumicino RM, Italy - DRoma S.Pietro, 00165 Roma RM, Italy
- ERoma Trastevere Railway Station, 00152 Roma RM, Italy
- FCesano Di Roma, 00123 Roma RM, Italy
Stops in Syracuse
- A
S. Teresa Longarini
Via Elorina, 129, 96100 Siracusa SR, Italy - BViale Paolo Orsi, 20, 96100 Siracusa SR, Italy
- C
Siracusa
Piazzale della Stazione Centrale, 21, 96100 Siracusa SR, Italy - D
Siracusa - Terminal Bus (Stazione FS)
Viale Teocrito, 68-74, 96100 Siracusa SR, Italy
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Frequently asked questions about travelling from Rome to Syracuse by bus or train
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much does a ticket from Rome to Syracuse cost?
The cheapest tickets from Rome to Syracuse start from R$276. The average price for this route is around R$462. Busbud recommends that you book your tickets in advance for a better chance of getting the lowest possible price.
How long is the journey from Rome to Syracuse?
The average trip duration from Rome to Syracuse is 16h 32m, covering a distance of 364 miles. The quickest vehicle can get you there in 11h 5m and is operated by Trenitalia.
Which companies operate the Rome to Syracuse route?
Several major companies operate on this route with 2 trips available per day, including services from FlixBus, Trenitalia.
What are the earliest and latest departure times from Rome to Syracuse?
The earliest service departs from Rome for Syracuse at 07:26. And the latest service departs at 23:55.
What are the CO₂ emissions for the journey from Rome to Syracuse?
A journey from Rome to Syracuse produces an estimated 14.6377375 kg of CO₂, making it a highly eco-friendly way to travel and a mode of transport recommended by Busbud.
Which is the best company from Rome to Syracuse?
According to Busbud customers, the highest-rated company on this route is Trenitalia, with an average rating of 3.9 out of 5 stars based on 58 reviews.
Which company has the best Wi-Fi from Rome to Syracuse?
According to reviews on Busbud, the company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which company offers the most punctual service from Rome to Syracuse?
According to Busbud traveller reviews, the most punctual company on this route is Trenitalia, with a punctuality rating of 4.6 out of 5 stars.
Which company has the cleanest vehicles from Rome to Syracuse?
According to Busbud traveller reviews, the company with the cleanest vehicles on this route is Trenitalia, with a cleanliness rating of 4.7 out of 5 stars.
Find the cheapest prices for buses and trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Rome to Syracuse was searched and found on 25 Apr 2026 with a price of R$313To save money and ensure you get the best seat, it's a good idea to buy your bus and train tickets from Rome to Syracuse, as early as possible.
You can expect to pay between R$313 and R$791 for a bus or train ticket from Rome to Syracuse based on the past 2 days. You can expect to find the lowest price for the trip at R$313 on 2026-04-25.
Usually Trenitalia will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
