Next available departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
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| Rome Tiburtina Bus Station | Terminal Bus Palermo | Cheapest | ||||
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| Termini | Palermo Centrale | Fastest | ||||
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| Rome Tiburtina Bus Station | Terminal Bus Palermo | No tags | ||||
 | Tiburtina | Terminal Bus Palermo | No tags | |||||
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| Termini | Palermo Centrale | No tags | ||||
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| Rome Tiburtina Bus Station | Terminal Bus Palermo | No tags | ||||
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| Rome Tiburtina Bus Station | Terminal Bus Palermo | No tags | ||||
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| Rome Tiburtina Bus Station | Terminal Bus Palermo | No tags |
Last refresh of the prices: Today at 12:00 AM CEST.
Compare 2 ways to travel from Rome to Palermo
Among the sustainable travel choices, the Bus stands out as a good way to reach Palermo. The journey takes about 15 hours 5 minutes and with fares starting at just PEN 81, it presents an excellent value for a comfortable ride.
Bus stations and stops in Rome and Palermo
Stops in Rome
- A
Termini
Piazza dei Cinquecento 1, 00185 Roma RM, Italy - B
Rome Tiburtina Bus Station
Largo Guido Mazzoni, 3, 00162 Roma, Italy - C
Rome Fiumicino Airport (FCO), Train station
Fiumicino Aeroporto, 00054 Fiumicino RM, Italy - D
Roma S. Pietro
Roma S.Pietro, 00165 Roma RM, Italy - F
Roma Trastevere
Roma Trastevere Railway Station, 00152 Roma RM, Italy
Stops in Palermo
- A
Palermo Centrale
Stazione Centrale - Cupani 3, 90123, 90123 Palermo PA, Italy - B
Vespri
Via del Vespro, 90127 Palermo PA, Italy - C
Terminal Bus Palermo
Via Tommaso Fazello, 16, 90123 Palermo PA, Italy - D
Francia
90146 Palermo PA, Italy - E
Guadagna
90124 Palermo PA, Italy - F
La Malfa
90146 Palermo PA, Italy
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Frequently asked questions about travelling from Rome to Palermo by bus or train
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is a ticket from Rome to Palermo?
The cheapest tickets from Rome to Palermo start at PEN 81. The average price for this route is around PEN 288. Busbud recommends booking your tickets in advance for a better chance of getting the lowest possible price.
How long is the journey from Rome to Palermo?
The average trip duration from Rome to Palermo is 13h 24m, covering a distance of 427 km. The quickest vehicle can get you there in 11h 36m and is operated by Trenitalia.
Which companies operate the Rome to Palermo route?
Several major companies operate on this route with 5 trips available per day, including services from FlixBus, Itabus, Autoservizi Salemi, Trenitalia.
What are the earliest and latest departure times from Rome to Palermo?
The earliest trip from Rome to Palermo departs at 01:20. The latest trip departs at 23:45.
What are the CO₂ emissions for the journey from Rome to Palermo?
A trip from Rome to Palermo generates an estimated 10.66415 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Which is the best company from Rome to Palermo?
According to Busbud customers, the highest-rated company on this route is Autoservizi Salemi, with an average rating of 4.3 out of 5 stars based on 558 reviews.
Which company has the best Wi-Fi from Rome to Palermo?
Based on reviews on Busbud, the company Autoservizi Salemi has the best Wi-Fi rating with a score of 3.9.
Which company has the most punctual service from Rome to Palermo?
According to Busbud traveller reviews, the most punctual company on this route is Trenitalia, with a punctuality rating of 4.4 out of 5 stars.
Which company has the cleanest vehicles from Rome to Palermo?
According to Busbud traveller reviews, the company with the cleanest vehicles on this route is Autoservizi Salemi, with a cleanliness rating of 4.7 out of 5 stars.
Find the cheapest prices for buses and trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Rome to Palermo was searched and found on 12 Sept 2026 with a price of PEN 103To save money and make sure you get the best seat, it's a good idea to buy your bus and train tickets from Rome to Palermo, as early as possible.
You can expect to pay between PEN 103 and PEN 476 for a bus or train ticket from Rome to Palermo based on the past 2 days. You can expect to find the lowest price for the trip at PEN 103 which is on 2026-09-12.
Usually Trenitalia will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Rome to Palermo?
The Bus is the cheapest travel choice for this destination
