Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Price and booking link |
|---|---|---|---|---|---|---|---|
FlixBus + Greyhound | Bus
| Florence, SC | Jackson (Union Station) | ||||
Greyhound + FlixBus | Bus
| Florence, SC | Jackson (Union Station) | ||||
Greyhound + FlixBus | Bus
| Florence, SC | Jackson (Union Station) | ||||
FlixBus + Greyhound | Bus
| Florence, SC | Jackson (Union Station) | ||||
FlixBus + Greyhound | Bus
| Bus station | Jackson (Union Station) |
Compare 2 ways to go from Florence to Jackson
Among the sustainable travel choices, the Bus stands out as a good way to reach Jackson. The journey takes about 22 hours and with fares starting at just CLP 90,918, it presents an excellent value for a comfortable ride.
Bus stations and stops in Florence and Jackson
Stops in Florence
- A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA - B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Stops in Jackson
- A
Jackson Bus Station
300 W Capitol St, Jackson, MS 39201, USA - B
Love's Travel Stop - Jackson
730 US-80, Flowood, MS 39232, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Florence, SC, US to Jackson, MS, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Florence to Jackson?
The cheapest bus tickets from Florence to Jackson start from CLP 90,918. The average price for this route is around CLP 112,269. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Florence to Jackson?
The average bus trip duration from Florence to Jackson is 22h, covering a distance of 615 miles (992 km). The quickest bus can get you there in 17h 20m and is operated by Greyhound.
Which bus companies service the Florence to Jackson route?
Several major bus companies operate on this route with 2 buses available per day.
What is the earliest and latest departure time for the bus from Florence to Jackson?
The earliest bus departs from Florence to Jackson at 5:45am. And the latest bus departs at 3:20pm.
What are the CO₂ emissions for the bus trip from Florence to Jackson?
A bus trip from Florence to Jackson generates an estimated 24.788375 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Florence, SC, US to Jackson, MS, US was searched and found on Sep 26, 2026 with a price of CLP 94,161To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Jackson, MS, US, as early as possible.
You can expect to pay from CLP 94,161 to CLP 106,784 for a bus ticket from Florence, SC, US to Jackson, MS, US based on the last 2 days. You can expect to find the cheapest price for the trip at CLP 94,161 which is on 2026-09-26.
What's the cheapest way to go from Florence, SC, US to Jackson, MS, US?
The Bus is the cheapest travel choice for this destination
