Bus from Lyon to Prague: Tickets & Schedules

Next bus departures

Next departures for Lyon to Prague on May 22
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
BlaBlaCar BusBus
Lyon - Gerland Bus Station
FlorencCheapestFastest

Last refresh of the prices: Yesterday at 5:16 PM CEST.

Get from Lyon to Prague

This route is served by bus only

The journey takes about 19 hours 5 minutes and with fares starting at just PLN 211, it presents an excellent value for a comfortable ride.

13bus per day
19h 5mAverage Duration
532 milesDistance
21kgCO₂ emissions

Frequently asked questions about traveling from Lyon to Prague by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Lyon to Prague?

    The cheapest bus tickets from Lyon to Prague start from PLN 211. The average price for this route is around PLN 352. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Lyon to Prague?

    The average bus trip duration from Lyon to Prague is 19h 5m, covering a distance of 532 miles (857 km). The quickest bus can get you there in 14h 40m and is operated by FlixBus.

  3. Which bus companies service the Lyon to Prague route?

    Several major bus companies operate on this route with 13 buses available per day, including services from FlixBus, BlaBlaCar Bus, RegioJet.

  4. What is the earliest and latest departure time for the bus from Lyon to Prague?

    The earliest bus departs from Lyon to Prague at 12:20am. And the latest bus departs at 11:30pm.

  5. What are the CO₂ emissions for the bus trip from Lyon to Prague?

    A bus trip from Lyon to Prague generates an estimated 21.421425 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

  6. What is the best bus company from Lyon to Prague?

    According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1076 reviews.

  7. Which bus company has the best Wi-Fi from Lyon to Prague?

    Based on reviews on Busbud, the bus company RegioJet has the best Wi-Fi rating with a score of 3.8.

  8. Which bus company has the most timely service from Lyon to Prague?

    According to Busbud traveler reviews, the most timely bus company on this route is RegioJet, with a punctuality rating of 4.0 out of 5 stars.

  9. Which bus company has the cleanest buses from Lyon to Prague?

    According to Busbud traveler reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.4 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/19
PLN 298
05/20
PLN 316
Today
PLN 244
05/22
PLN 557
05/23
PLN 357
05/24
No data
05/25
PLN 469
05/26
No data
busbud logoThe cheapest trip from Lyon to Prague was searched and found on May 21, 2026 with a price of PLN 244

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lyon to Prague, as early as possible.

You can expect to pay from PLN 244 to PLN 581 for a bus ticket from Lyon to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at PLN 357 which is on 2026-05-23.

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