Bus from Palermo to Rome: Tickets & Schedules

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Next bus departures

Next departures for Palermo to Rome on October 1
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Flixbus Bus
  • Wifi
  • Toilet
  • Power outlets
Terminal Bus Palermo
Rome Tiburtina Bus StationCheapest
Autoservizi SalemiBus
Terminal Bus Palermo
TiburtinaFastest
Flixbus Bus
  • Wifi
  • Toilet
  • Power outlets
Terminal Bus Palermo
Aeroporto Ciampino Airport (CIA)No tags
Flixbus Bus
  • Wifi
  • Toilet
  • Power outlets
Terminal Bus Palermo
Rome Fiumicino AirportNo tags
Flixbus Bus
  • Wifi
  • Toilet
  • Power outlets
Terminal Bus Palermo
Rome Fiumicino AirportNo tags
Flixbus Bus
  • Wifi
  • Toilet
  • Power outlets
Terminal Bus Palermo
Rome Tiburtina Bus StationNo tags
Flixbus Bus
  • Wifi
  • Toilet
  • Power outlets
Terminal Bus Palermo
Rome Tiburtina Bus StationNo tags
Flixbus Bus
  • Wifi
  • Toilet
  • Power outlets
Terminal Bus Palermo
Rome AnagninaNo tags

Last refresh of the prices: Yesterday at 10:49 PM CEST.

Compare 2 ways to go from Palermo to Rome

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach Rome. The journey takes about 11 hours 29 minutes and with fares starting at just CLP 40,513, it presents an excellent value for a comfortable ride.

1train per day
11h 29mAverage Duration
266 milesDistance
10kgCO₂ emissions
Bus
Average PriceCLP 15,826 - CLP 224,594Average Duration16h 30m
11kg CO₂e
Train
Average PriceCLP 40,513 - CLP 273,558Average Duration11h 29m
10kg CO₂e

Frequently asked questions about traveling from Palermo to Rome by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Palermo to Rome?

    The cheapest bus tickets from Palermo to Rome start from CLP 15,826. The average price for this route is around CLP 55,969. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Palermo to Rome?

    The average bus trip duration from Palermo to Rome is 16h 30m, covering a distance of 264 miles (425 km). The quickest bus can get you there in 12h 15m and is operated by Autoservizi Salemi.

  3. Which bus companies service the Palermo to Rome route?

    Several major bus companies operate on this route with 7 buses available per day, including services from FlixBus, Itabus, Autoservizi Salemi.

  4. What is the earliest and latest departure time for the bus from Palermo to Rome?

    The earliest bus departs from Palermo to Rome at 9:10am. And the latest bus departs at 9:10pm.

  5. What are the CO₂ emissions for the bus trip from Palermo to Rome?

    A bus trip from Palermo to Rome generates an estimated 10.606275 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

  6. What is the best bus company from Palermo to Rome?

    According to Busbud customers, the highest-rated bus company on this route is Autoservizi Salemi, with an average rating of 4.3 out of 5 stars based on 563 reviews.

  7. Which bus company has the best Wi-Fi from Palermo to Rome?

    Based on reviews on Busbud, the bus company Autoservizi Salemi has the best Wi-Fi rating with a score of 3.9.

  8. Which bus company has the most timely service from Palermo to Rome?

    According to Busbud traveler reviews, the most timely bus company on this route is Autoservizi Salemi, with a punctuality rating of 4.3 out of 5 stars.

  9. Which bus company has the cleanest buses from Palermo to Rome?

    According to Busbud traveler reviews, the bus company with the cleanest buses on this route is Autoservizi Salemi, with a cleanliness rating of 4.7 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/28
CLP 69,889
09/29
CLP 101,421
Today
CLP 69,580
10/01
CLP 51,589
10/02
CLP 54,492
10/03
CLP 34,765
10/04
CLP 54,492
10/05
CLP 29,546
busbud logoThe cheapest trip from Palermo to Rome was searched and found on Oct 5, 2026 with a price of CLP 29,546

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Palermo to Rome, as early as possible.

You can expect to pay from CLP 29,546 to CLP 157,699 for a bus ticket from Palermo to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at CLP 29,546 which is on 2026-10-05.

What's the cheapest way to go from Palermo to Rome?

busbud logoThe Bus is the cheapest travel choice for this destination

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