Next bus departures

Next departures for Plzeň to Brno on September 25
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus Wifi Toilet Power outlets	1:50am	Husova, 2713/60	4h	5:50am	Hotelu Grand	CheapestFastest
Bus	5:30pm	Pilsen CAN	4h 20m	9:50pm	hotel GRAND, Brno	No tags
Bus Wifi Toilet Power outlets	6:45am	Husova, 2713/60	4h 35m	11:20am	Hotelu Grand	No tags
Bus	5:35pm	Plzeň Divadlo Alfa	4h 15m	9:50pm	hotel GRAND, Brno	No tags
Bus Wifi Toilet Power outlets	6:50am	Rokycanská 1171/6	4h 30m	11:20am	Hotelu Grand	No tags

Last refresh of the prices: Today at 12:28 PM CEST.

Compare 2 ways to go from Plzeň to Brno

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Brno. The journey takes about 4 hours 20 minutes and with fares starting at just CHF 11, it presents an excellent value for a comfortable ride.

3bus per day

4h 20mAverage Duration

150 milesDistance

6kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average PriceCHF 11 - CHF 145	Average Duration4h 20m	CO₂ emissions 6kg CO₂e
Train	Average PriceCHF 89 - CHF 90	Average Duration4h 13m	CO₂ emissions 6kg CO₂e

Bus stations and stops in Plzeň and Brno

Stops in Plzeň

A
Rokycanská 1171/6
Rokycanská 1171/6, Lobzy 301 00 Plzeň-Plzeň 4, Czech Republic
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B
Plzeň Autobusová Zastávka
Husova 2713/60, 301 00 Plzeň 3, Czech Republic
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C
nám. Republiky 358/33
nám. Republiky 358/33, Vnitřní Město, 301 00 Plzeň-Plzeň 3, Czech Republic
D
Rokycanská 1328/112
Rokycanská 1328/112, Doubravka, 312 00 Plzeň-Plzeň 4, Czech Republic
E
Plzen
Přeštická 1761/4, Jižní Předměstí, 301 00 Plzeň-Plzeň 3, Czechia

Stops in Brno

A
Hotelu Grand
Benešova 603/2, Brno-město, 602 00 Brno-Brno-střed, Czech Republic
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B
Hlavní nádraží
Nádražní 418/1, Brno-město, 602 00 Brno-Brno-střed, Czechia
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C
Brno Bus Station
Brno Bus Station, ÚAN Zvonařka, 602 00 Brno-střed, Czechia
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D
ÚAN Zvonařka
Zvonařka 411, Trnitá, 602 00 Brno-Brno-střed, Czech Republic
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E
Židenice
Lazaretní 610/11, 615 00 Brno-Brno-Židenice, Czechia
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F
Vídeňská 98
Vídeňská 98, 619 00 Brno-jih, Czechia

Compare bus companies

FlixBus

3.5/515,863 reviews

Staff4.2

Timeliness4.0

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

A-Express

AMI-TOUR

Slovak Lines

4.5/5187 reviews

Staff4.8

Timeliness4.9

Cleanliness5.0

Wifi4.3

CZ bus companies:FlixBus, BlaBlaCar Bus, Deutsche Bahn, Sindbad, Ecolines, KLR Bus, RegioJet

Frequently asked questions about traveling from Plzeň to Brno by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Plzeň to Brno?
The cheapest bus tickets from Plzeň to Brno start from CHF 11. The average price for this route is around CHF 22. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Plzeň to Brno?
The average bus trip duration from Plzeň to Brno is 4h 20m, covering a distance of 150 miles (242 km). The quickest bus can get you there in 4h and is operated by FlixBus.
Which bus companies service the Plzeň to Brno route?
Several major bus companies operate on this route with 3 buses available per day, including services from FlixBus, A-Express, AMI-TOUR, Slovak Lines.
What is the earliest and latest departure time for the bus from Plzeň to Brno?
The earliest bus departs from Plzeň to Brno at 12:00am. And the latest bus departs at 11:55pm.
What are the CO₂ emissions for the bus trip from Plzeň to Brno?
A bus trip from Plzeň to Brno generates an estimated 6.047675 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Plzeň to Brno?
According to Busbud customers, the highest-rated bus company on this route is Slovak Lines, with an average rating of 4.5 out of 5 stars based on 187 reviews.
Which bus company has the best Wi-Fi from Plzeň to Brno?
Based on reviews on Busbud, the bus company Slovak Lines has the best Wi-Fi rating with a score of 4.3.
Which bus company has the most timely service from Plzeň to Brno?
According to Busbud traveler reviews, the most timely bus company on this route is Slovak Lines, with a punctuality rating of 4.9 out of 5 stars.
Which bus company has the cleanest buses from Plzeň to Brno?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is Slovak Lines, with a cleanliness rating of 5.0 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

09/22

CHF 25

09/23

CHF 11

Today

CHF 11

09/25

CHF 13

09/26

No data

09/27

No data

09/28

No data

09/29

No data

The cheapest trip from Plzeň to Brno was searched and found on Sep 24, 2026 with a price of CHF 11

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Plzeň to Brno, as early as possible.

You can expect to pay from CHF 11 to CHF 143 for a bus ticket from Plzeň to Brno based on the last 2 days. You can expect to find the cheapest price for the trip at CHF 13 which is on 2026-09-25.