Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus
| Jacksonville Bus Station | Indianapolis (W Vermont St) | Cheapest | ||||
FlixBus + Greyhound Lines, Inc. | Bus
| Jacksonville Bus Station | Indianapolis Bus Station | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus
| Jacksonville Bus Station | Indianapolis Bus Station | No tags | ||||
 | Bus
| Jacksonville Bus Station | Indianapolis Bus Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus
| Jacksonville Bus Station | Indianapolis Bus Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus
| Jacksonville Bus Station | Indianapolis Bus Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus
| Jacksonville Bus Station | Indianapolis (W Vermont St) | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus
| Jacksonville Bus Station | Indianapolis (W Vermont St) | No tags |
Last refresh of the prices: Yesterday at 4:52 PM EDT.
Compare 2 ways to go from Jacksonville to Indianapolis
Among the sustainable travel choices, the Bus stands out as a good way to reach Indianapolis. The journey takes about 22 hours 30 minutes, and with fares starting at just ZAR 1,698, it presents an excellent value for a comfortable ride.
Bus stations and stops in Jacksonville and Indianapolis
Stops in Jacksonville
- A
Jacksonville Amtrak Station
3570 Clifford Ln, Jacksonville, FL 32209, USA - B
W Forsyth St
1111 W Forsyth St, Jacksonville, FL 32204, USA - C
Kings Avenue Station
1003 Kings Avenue, Jacksonville, FL 32207 - D
JRTC Greyhound Bus Station
111 W. Forsyth St, Jacksonville, FL 32202, USA
Compare bus companies
Frequently asked questions about travelling from Jacksonville, FL to Indianapolis by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Jacksonville to Indianapolis?
The cheapest bus tickets from Jacksonville to Indianapolis start from ZAR 1,698. The average price for this route is around ZAR 2,314. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Jacksonville to Indianapolis?
The average bus travel time from Jacksonville to Indianapolis is 22h 30m, covering a distance of 1128 km. The quickest bus can get you there in 20h 55m and is operated by Greyhound.
Which bus companies service the Jacksonville to Indianapolis route?
What are the earliest and latest departure times for the bus from Jacksonville to Indianapolis?
The earliest bus departs from Jacksonville to Indianapolis at 9:05am. And the latest bus departs at 11:15pm.
What are the CO₂ emissions for the bus trip from Jacksonville to Indianapolis?
A bus trip from Jacksonville to Indianapolis generates an estimated 28.179425 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Jacksonville to Indianapolis?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 88168 reviews.
Which bus company has the best Wi-Fi from Jacksonville to Indianapolis?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Jacksonville to Indianapolis?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Jacksonville to Indianapolis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Jacksonville, FL to Indianapolis was searched and found on Sep 30, 2026 with a price of ZAR 1,678To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jacksonville, FL to Indianapolis, as early as possible.
You can expect to pay from ZAR 1,678 to ZAR 2,842 for a bus ticket from Jacksonville, FL to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at ZAR 1,764 which is on 2026-10-06.
What's the cheapest way to go from Jacksonville, FL to Indianapolis?
The Bus is the cheapest travel choice for this destination
