Next bus departures

Next departures for Jacksonville to Indianapolis on August 10
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	4:30pm	Jacksonville Bus Station	19h 40m	12:10pm	Indianapolis Bus Station	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	9:25pm	Jacksonville Bus Station	19h 20m	4:45pm	Indianapolis Bus Station	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	9:05am	Jacksonville Bus Station	19h 50m	4:55am	Indianapolis Bus Station	No tags
	Bus	10:00am	Jacksonville Bus Station	23h 30m	9:30am	Indianapolis Bus Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	11:15pm	Jacksonville Bus Station	1d 5h	4:55am	Indianapolis Bus Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	10:00am	Jacksonville Bus Station	22h	8:00am	Indianapolis (W Vermont St)	No tags
FlixBus + Greyhound Lines, Inc.	Bus	9:25pm	Jacksonville Bus Station	1d	9:45pm	Indianapolis (W Vermont St)	No tags

Last refresh of the prices: Last Thursday at 11:14 AM EDT.

Compare 2 ways to go from Jacksonville to Indianapolis

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Indianapolis. The journey takes about 22 hours and with fares starting at just TRY 4,212, it presents an excellent value for a comfortable ride.

8bus per day

22hAverage Duration

698 milesDistance

28kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average PriceTRY 4,212 - TRY 15,163	Average Duration22h	CO₂ emissions 28kg CO₂e
Train	Average PriceTRY 14,329 - TRY 30,015	Average Duration1d 13h	CO₂ emissions 102kg CO₂e

Bus stations and stops in Jacksonville and Indianapolis

Stops in Jacksonville

A
Jacksonville Amtrak Station
3570 Clifford Ln, Jacksonville, FL 32209, USA
Visit page
B
W Forsyth St
1111 W Forsyth St, Jacksonville, FL 32204, USA
C
Kings Avenue Station
1003 Kings Avenue, Jacksonville, FL 32207
D
JRTC Greyhound Bus Station
111 W. Forsyth St, Jacksonville, FL 32202, USA

Stops in Indianapolis

A
Greyhound Amtrak Station
350 S Illinois St, Indianapolis, IN 46225
Visit page

Compare bus companies

Greyhound

3.5/588,035 reviews

Staff3.6

Timeliness3.0

Cleanliness3.4

Wifi2.5

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/515,039 reviews

Staff4.1

Timeliness4.0

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies:FlixBus, Greyhound, Futura, Elite, Chihuahuenses, Tufesa, Adirondack Trailways

Frequently asked questions about traveling from Jacksonville, FL to Indianapolis by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Jacksonville to Indianapolis?
The cheapest bus tickets from Jacksonville to Indianapolis start from TRY 4,212. The average price for this route is around TRY 7,585. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Jacksonville to Indianapolis?
The average bus trip duration from Jacksonville to Indianapolis is 22h, covering a distance of 698 miles (1126 km). The quickest bus can get you there in 23h and is operated by FlixBus.
Which bus companies service the Jacksonville to Indianapolis route?
Several major bus companies operate on this route with 8 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from Jacksonville to Indianapolis?
The earliest bus departs from Jacksonville to Indianapolis at 9:05am. And the latest bus departs at 11:15pm.
What are the CO₂ emissions for the bus trip from Jacksonville to Indianapolis?
A bus trip from Jacksonville to Indianapolis generates an estimated 28.136975000000003 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Jacksonville to Indianapolis?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 88023 reviews.
Which bus company has the best Wi-Fi from Jacksonville to Indianapolis?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Jacksonville to Indianapolis?
According to Busbud traveler reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Jacksonville to Indianapolis?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

08/06

TRY 13,591

08/07

TRY 11,684

Today

TRY 9,875

08/09

TRY 10,364

08/10

TRY 6,893

08/11

TRY 5,280

08/12

TRY 5,182

08/13

No data

The cheapest trip from Jacksonville, FL to Indianapolis was searched and found on Aug 12, 2026 with a price of TRY 5,182

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jacksonville, FL to Indianapolis, as early as possible.

You can expect to pay from TRY 5,182 to TRY 13,591 for a bus ticket from Jacksonville, FL to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at TRY 5,182 which is on 2026-08-12.