Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Rome Tiburtina Bus Station | Prague (Central Bus Station Florenc) | Cheapest | ||||
| Bus | Rome Anagnina | Prague (Main Railway Station) | Fastest | ||||
| Bus | Aeroporto Ciampino Airport (CIA) | PRG Airport | No tags | ||||
| Bus | Aeroporto Ciampino Airport (CIA) | PRG Airport | No tags | ||||
| Bus | Rome Tiburtina Bus Station | PRG Airport | No tags | ||||
| Bus | Rome Tiburtina Bus Station | PRG Airport | No tags | ||||
| Bus | Rome Tiburtina Bus Station | PRG Airport | No tags | ||||
| Bus | Rome Tiburtina Bus Station | PRG Airport | No tags |
Last refresh of the prices: Yesterday at 7:23 AM CEST.
Get from Rome to Prague
The journey takes about 1 day, 40 minutes, and with fares starting at just JP¥11,132, it presents an excellent value for a comfortable ride.
Bus stations and stops in Rome and Prague
Stops in Rome
- A
Rome Tiburtina Bus Station
Largo Guido Mazzoni, 3, 00162 Roma, Italy - D
Castro Pretorio
Viale Castro Pretorio 76, 00185 Roma, Italy - E
Roma
- F
Anagnina
Via Vincenzo Giudice, 00173 Roma RM, Italy
Stops in Prague
- A
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic - B
PRG Airport
Aviatická, 161 08, Praha 6, Czechia - C
Florenc
Křižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic - D
Černý Most
Chlumecká, 198 00 Praha 20, Czech Republic - E
Tomíčkova
Tomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia - F
Hlavní nádraží
300/8 Wilsonova, 110 00 Praha, Czechia
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Frequently asked questions about travelling from Rome to Prague by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Rome to Prague?
The cheapest bus tickets from Rome to Prague start from JP¥11,132. The average price for this route is around JP¥26,493. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Rome to Prague?
The average bus travel time from Rome to Prague is 1d , covering a distance of 928 km. The quickest bus can get you there in 19h 55m and is operated by FlixBus.
Which bus companies service the Rome to Prague route?
What are the earliest and latest departure times for the bus from Rome to Prague?
The earliest bus departs from Rome to Prague at 1:05am. And the latest bus departs at 11:50pm.
What are the CO₂ emissions for the bus trip from Rome to Prague?
A bus trip from Rome to Prague generates an estimated 23.181075 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Rome to Prague?
According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1102 reviews.
Which bus company has the best Wi-Fi from Rome to Prague?
Based on Busbud reviews, the bus company RegioJet has the highest Wi-Fi rating with a score of 3.8.
Which bus company has the best on-time performance from Rome to Prague?
According to Busbud traveller reviews, the most punctual bus company on this route is RegioJet, with a punctuality rating of 4.1 out of 5 stars.
Which bus company has the cleanest buses from Rome to Prague?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.4 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Rome to Prague was searched and found on Aug 12, 2026 with a price of JP¥15,436To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rome to Prague, as early as possible.
You can expect to pay from JP¥15,436 to JP¥54,019 for a bus ticket from Rome to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at JP¥15,457 which is on 2026-08-16.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
