Next train departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
vlexx + Deutsche Bahn + DB Regio Südost + Ceske Drahy | Train | Mainz Central Train Station | Hlavní nádraží | Cheapest | ||||
vlexx + Deutsche Bahn | Train | Mainz Central Train Station | Hlavní nádraží | Fastest | ||||
Deutsche Bahn + Deutsche Bahn + DB Regio Bayern + alex - Die Länderbahn | Train | Mainz Central Train Station | Hlavní nádraží | No tags | ||||
Deutsche Bahn + DB Regio Südost + Ceske Drahy | Train | Mainz Central Train Station | Hlavní nádraží | No tags | ||||
Deutsche Bahn + Deutsche Bahn + DB Regio Bayern + alex - Die Länderbahn | Train | Mainz Central Train Station | Hlavní nádraží | No tags | ||||
Deutsche Bahn + DB Regio Südost + Ceske Drahy | Train | Mainz Central Train Station | Hlavní nádraží | No tags | ||||
Deutsche Bahn + Deutsche Bahn + DB Regio Bayern + alex - Die Länderbahn | Train | Mainz Central Train Station | Hlavní nádraží | No tags | ||||
Deutsche Bahn + DB Regio Südost + Ceske Drahy | Train | Mainz Central Train Station | Hlavní nádraží | No tags |
Last refresh of the prices: Today at 9:42 AM CEST.
Compare 2 ways to go from Mainz to Prague
Among the sustainable travel choices, the Bus stands out as a good way to reach Prague. The journey takes about 11 hours 40 minutes, and with fares starting at just PEN 139, it presents an excellent value for a comfortable ride.
Where are the popular train stations and stops in Mainz and Prague?
Prague
- A
Hlavní nádraží
300/8 Wilsonova, 110 00 Praha, Czechia - B
Praha hl.n
Prague Main Railway Station, 120 00 Praha-Praha 2, Czechia - C
PRG Airport
Aviatická, 161 08, Praha 6, Czechia - D
Holešovice
Praha-Holešovice, Partyzánská 1546/26, 170 00 Praha 7-Holešovice, Czechia - E
Florenc
Křižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic - F
Černý Most
Chlumecká, 198 00 Praha 20, Czech Republic
Train companies
Based on 12 reviews, the company was rated 4 stars on Busbud. Travellers were especially satisfied with the ticket access and the departure location but often complained with the Wi‑Fi. Deutsche Bahn ticket prices on this trip start at PEN 940
Frequently asked questions about travelling from Mainz to Prague by train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the train ticket from Mainz to Prague?
The cheapest train tickets from Mainz to Prague start at PEN 147. The average price for this train route is around PEN 559. Busbud recommends booking your tickets in advance to increase your chances of getting the lowest possible price.
How long is the train ride from Mainz to Prague?
The average train trip from Mainz to Prague takes 9h 15m and covers 442 km. The quickest train gets you there in 8h 43m and is operated by Deutsche Bahn.
Which train operators serve the Mainz to Prague route?
Several major train operators serve this route, with 9 trains available per day.
What are the earliest and latest departure times for the train from Mainz to Prague?
The earliest train from Mainz to Prague departs at 6:02am. The latest train departs at 11:23pm.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mainz to Prague was searched and found on Oct 2, 2026 with a price of PEN 826To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Mainz to Prague, as early as possible.
