Next departures for Prague to Brussels on October 8
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Wi‑Fi
Toilet
Power outlets
Prague (Central Bus Station Florenc)
Brussels North Train Station
CheapestFastest
Bus
Florenc
Brussels-South (Gare du Midi)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Prague (Central Bus Station Florenc)
Brussels Airport BRU (Parking P14)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Prague (Central Bus Station Florenc)
Brussels Airport BRU (Parking P14)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Prague (Central Bus Station Florenc)
Brussels Airport BRU (Parking P14)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Prague (Central Bus Station Florenc)
Brussels Airport BRU (Parking P14)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Prague (Main Railway Station)
Brussels Airport BRU (Parking P14)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Prague (Main Railway Station)
Brussels Airport BRU (Parking P14)
No tags
Next departures for Prague to Brussels on October 9
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Toilet
Power outlets
Florenc
Brussels South (Gare du Midi)
CheapestFastest
Next departures for Prague to Brussels on October 10
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Wi‑Fi
Toilet
Power outlets
Prague (Main Station - parking)
Brussels North Train Station
Cheapest
Bus
Wi‑Fi
Toilet
Power outlets
Prague (Central Bus Station Florenc)
Brussels North Train Station
Fastest
Bus
Wi‑Fi
Toilet
Power outlets
Prague (Central Bus Station Florenc)
Brussels Airport BRU (Parking P14)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Prague (Central Bus Station Florenc)
Brussels Airport BRU (Parking P14)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Prague (Central Bus Station Florenc)
Brussels Airport BRU (Parking P14)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Prague (Central Bus Station Florenc)
Brussels Airport BRU (Parking P14)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Prague (Main Railway Station)
Brussels Airport BRU (Parking P14)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Prague (Main Railway Station)
Brussels Airport BRU (Parking P14)
No tags
Next departures for Prague to Brussels on October 11
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Wi‑Fi
Toilet
Power outlets
Prague (Main Station - parking)
Brussels North Train Station
Cheapest
Bus
Wi‑Fi
Toilet
Power outlets
Prague (Central Bus Station Florenc)
Brussels North Train Station
Fastest
Bus
Florenc
Brussels-South (Gare du Midi)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Prague (Central Bus Station Florenc)
Brussels Airport BRU (Parking P14)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Prague (Central Bus Station Florenc)
Brussels Airport BRU (Parking P14)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Prague (Central Bus Station Florenc)
Brussels Airport BRU (Parking P14)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Prague (Central Bus Station Florenc)
Brussels Airport BRU (Parking P14)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Prague (Main Railway Station)
Brussels Airport BRU (Parking P14)
No tags
Next departures for Prague to Brussels on October 12
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Wi‑Fi
Toilet
Power outlets
Prague (Central Bus Station Florenc)
Brussels South (Gare du Midi)
Cheapest
Bus
Wi‑Fi
Toilet
Power outlets
Prague (Central Bus Station Florenc)
Brussels North Train Station
Fastest
Bus
Wi‑Fi
Toilet
Power outlets
Prague (Central Bus Station Florenc)
Brussels Airport BRU (Parking P14)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Prague (Main Railway Station)
Brussels Airport BRU (Parking P14)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Prague (Main Railway Station)
Brussels Airport BRU (Parking P14)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Prague (Main Railway Station)
Brussels Airport BRU (Parking P14)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Prague (Main Station - parking)
Brussels Airport BRU (Parking P14)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Prague (Main Station - parking)
Brussels Airport BRU (Parking P14)
No tags
Next departures for Prague to Brussels on October 13
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Toilet
Power outlets
Florenc
Brussels South (Gare du Midi)
CheapestFastest
Last refresh of the prices: Yesterday at 4:07 AM CEST.
Compare 2 ways to go from Prague to Brussels
We recommend taking the bus
Among the sustainable travel choices, the Bus stands out as a good way to reach Brussels. The journey takes about 17 hours 55 minutes, and with fares starting at just ZAR 582, it presents an excellent value for a comfortable ride.
Based on 16115 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi‑Fi. FlixBus ticket prices on this trip start at ZAR 582
Based on 1115 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the departure location and the ticket access but often complained with the Wi‑Fi. RegioJet ticket prices on this trip start at ZAR 754
Based on 12967 reviews, the company was rated 3.7 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the Wi‑Fi. BlaBlaCar Bus ticket prices on this trip start at ZAR 1,234
Frequently asked questions about travelling from Prague to Brussels by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Prague to Brussels?
The cheapest bus tickets from Prague to Brussels start from ZAR 582. The average price for this route is around ZAR 1,176. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Prague to Brussels?
The average bus travel time from Prague to Brussels is 17h 55m, covering a distance of 714 km. The quickest bus can get you there in 12h and is operated by RegioJet.
Which bus companies service the Prague to Brussels route?
Several major bus companies operate on this route with 39 buses available per day, including services from FlixBus, RegioJet, BlaBlaCar Bus.
What are the earliest and latest departure times for the bus from Prague to Brussels?
The earliest bus departs from Prague to Brussels at 12:10am. And the latest bus departs at 11:50pm.
What are the CO₂ emissions for the bus trip from Prague to Brussels?
A bus trip from Prague to Brussels generates an estimated 17.825725 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Prague to Brussels?
According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1114 reviews.
Which bus company has the best Wi-Fi from Prague to Brussels?
Based on Busbud reviews, the bus company RegioJet has the highest Wi-Fi rating with a score of 3.7.
Which bus company has the best on-time performance from Prague to Brussels?
According to Busbud traveller reviews, the most punctual bus company on this route is RegioJet, with a punctuality rating of 4.1 out of 5 stars.
Which bus company has the cleanest buses from Prague to Brussels?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.3 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
10-06
ZAR 981
10-07
ZAR 939
Today
ZAR 1,063
10-09
ZAR 786
10-10
ZAR 996
10-11
ZAR 1,261
10-12
ZAR 884
10-13
ZAR 786
The cheapest trip from Prague to Brussels was searched and found on Oct 13, 2026 with a price of ZAR 786
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Brussels, as early as possible.
You can expect to pay from ZAR 786 to ZAR 3,478 for a bus ticket from Prague to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at ZAR 786 which is on 2026-10-13.
The cheapest trip from Prague to Brussels was searched and found on Oct 13, 2026 with a price of ZAR 786
