How much is the bus ticket from Prague to Brussels?

The cheapest coach tickets from Prague to Brussels start from PLN 167. The average price for this route is around PLN 322. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus journey from Prague to Brussels?

The average bus journey time from Prague to Brussels is 18h 25m, covering a distance of 443 miles. The fastest bus can take you there in 12h and is operated by RegioJet .

Which bus companies service the Prague to Brussels route?

Several major bus companies operate on this route with 19 buses available per day, including services from FlixBus , BlaBlaCar Bus , RegioJet .

What is the earliest and latest departure time for the bus from Prague to Brussels?

The earliest bus departs from Prague to Brussels at 01:45. And the latest bus departs at 23:50.

What are the CO₂ emissions for the bus trip from Prague to Brussels?

A bus journey from Prague to Brussels produces an estimated 17.826275000000003 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.

Which is the best bus company from Prague to Brussels?

According to Busbud customers, the highest-rated bus company on this route is RegioJet , with an average rating of 4.1 out of 5 stars based on 1074 reviews.

Which company has the best Wi-Fi from Prague to Brussels?

Based on Busbud reviews, the bus company RegioJet has the best Wi-Fi rating with a score of 3.8.

Which bus company offers the most punctual service from Prague to Brussels?

According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus , with a punctuality rating of 4.0 out of 5 stars.

Which bus company has the cleanest buses from Prague to Brussels?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet , with a cleanliness rating of 4.4 out of 5 stars.

Bus Prague to Brussels from PLN 179 | Refundable Tickets

Next bus departures

Next departures from Prague to Brussels on 17 May
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	19:00	Florenc	18h 30m	13:30	Brussels-South (Gare du Midi)	CheapestFastest

Next departures from Prague to Brussels on 19 May
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	11:05	Prague (Central Bus Station Florenc)	13h 20m	00:25	Brussels North Train Station	Cheapest
Bus	18:00	Florenc	12h	06:00	Brussels South (Gare du Midi)	Fastest
Bus	22:00	Prague (Central Bus Station Florenc)	23h 15m	21:15	Brussels Airport BRU	No tags
Bus	04:00	Prague (Main Railway Station)	22h 5m	02:05	Brussels Airport BRU	No tags
Bus	05:50	Prague (Main Railway Station)	1d	06:35	Brussels Airport BRU	No tags

Next departures from Prague to Brussels on 21 May
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	19:00	Florenc	18h 30m	13:30	Brussels-South (Gare du Midi)	CheapestFastest

Last refresh of the prices: Yesterday at 23:01 CEST.

Compare 2 ways to travel from Prague to Brussels

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach Brussels. The journey takes about 15 hours 22 minutes and with fares starting at just PLN 303, it presents an excellent value for a comfortable ride.

2train per day

15h 22mAverage duration

446 milesDistance

17kgCO₂ emissions

	Average price	Average duration	CO₂ emissions	Actions
Bus	Average pricePLN 167 - PLN 966	Average duration18h 25m	CO₂ emissions 18kg CO₂e
Train	Average pricePLN 303 - PLN 1,441	Average duration15h 22m	CO₂ emissions 17kg CO₂e

Where are the popular stops in Prague and Brussels?

Stops in Prague

A
Černý Most
Chlumecká, 198 00 Praha 20, Czech Republic
Visit page
B
PRG Airport
Aviatická, 161 08, Praha 6, Czechia
Visit page
C
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic
D
Florenc
Křižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
Visit page
E
Tomíčkova
Tomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
Visit page
F
Hlavní nádraží
300/8 Wilsonova, 110 00 Praha, Czechia
Visit page

Stops in Brussels

A
Brussels South (Gare du Midi)
Rue de France 85, 1060 Saint-Gilles, Belgium
Visit page
B
Brux-Nord
Boulevard Simon Bolivar 7, 1030 Schaerbeek, Belgium
Visit page
C
Centrale
Rue de Loxum 5, 1000 Bruxelles, Belgium
D
Congrès
Pachecolaan 5, 1000 Brussel, Belgium
Visit page

Compare companies

FlixBus

3.5/512,651 reviews

Staff4.2

Timeliness4.0

Cleanliness4.1

Wi‑Fi2.7

BlaBlaCar Bus

3.7/511,792 reviews

Staff4.4

Timeliness3.6

Cleanliness4.3

Wi‑Fi2.6

RegioJet

4.1/51,075 reviews

Staff4.5

Timeliness4.0

Cleanliness4.4

Wi‑Fi3.8

BE bus companies:FlixBus, BlaBlaCar Bus, Sindbad, Ecolines, KLR Bus, RegioJet, Agat

Frequently asked questions about travelling by bus from Prague to Brussels

Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.

How much is the bus ticket from Prague to Brussels?
The cheapest coach tickets from Prague to Brussels start from PLN 167. The average price for this route is around PLN 322. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Prague to Brussels?
The average bus journey time from Prague to Brussels is 18h 25m, covering a distance of 443 miles. The fastest bus can take you there in 12h and is operated by RegioJet.
Which bus companies service the Prague to Brussels route?
Several major bus companies operate on this route with 19 buses available per day, including services from FlixBus, BlaBlaCar Bus, RegioJet.
What is the earliest and latest departure time for the bus from Prague to Brussels?
The earliest bus departs from Prague to Brussels at 01:45. And the latest bus departs at 23:50.
What are the CO₂ emissions for the bus trip from Prague to Brussels?
A bus journey from Prague to Brussels produces an estimated 17.826275000000003 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Prague to Brussels?
According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1074 reviews.
Which company has the best Wi-Fi from Prague to Brussels?
Based on Busbud reviews, the bus company RegioJet has the best Wi-Fi rating with a score of 3.8.
Which bus company offers the most punctual service from Prague to Brussels?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Prague to Brussels?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.4 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

15/05

PLN 224

16/05

PLN 321

Today

PLN 558

18/05

PLN 194

19/05

PLN 183

20/05

No data

21/05

PLN 384

22/05

PLN 225

The cheapest trip from Prague to Brussels was searched and found on 19 May 2026 with a price of PLN 183

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Brussels as early as possible.

You can expect to pay from PLN 183 to PLN 878 for a bus ticket from Prague to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at PLN 183, which is on 2026-05-19.