Next train departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Brussels South/Midi Train Station | Hlavní nádraží | Cheapest | ||||
| Train | Brussels South/Midi Train Station | Hlavní nádraží | Fastest | ||||
| Train | Brussels South/Midi Train Station | Hlavní nádraží | No tags | ||||
| Train | Brussels South/Midi Train Station | Hlavní nádraží | No tags | ||||
| Train | Brussels South/Midi Train Station | Hlavní nádraží | No tags |
Last refresh of the prices: Today at 3:12 PM CEST.
Compare 2 ways to go from Brussels to Prague
Among the sustainable travel choices, the Bus stands out as a good way to reach Prague. The journey takes about 18 hours 35 minutes, and with fares starting at just ARS 51,255, it presents an excellent value for a comfortable ride.
Where are the popular train stations and stops in Brussels and Prague?
Brussels
- A
Brussels South (Gare du Midi)
Rue de France 85, 1060 Saint-Gilles, Belgium - B
Bruxelles / Brussels Central
Brussel-Centraal, Carrefour de l'Europe, 1000 Bruxelles, Belgium
Prague
- A
Hlavní nádraží
300/8 Wilsonova, 110 00 Praha, Czechia - B
Praha hl.n
Prague Main Railway Station, 120 00 Praha-Praha 2, Czechia - C
PRG Airport
Aviatická, 161 08, Praha 6, Czechia - D
Florenc
Křižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic - E
Holešovice
Praha-Holešovice, Partyzánská 1546/26, 170 00 Praha 7-Holešovice, Czechia - F
Černý Most
Chlumecká, 198 00 Praha 20, Czech Republic
Train companies
Based on 10 reviews, the company was rated 3.8 stars on Busbud. Travellers were especially satisfied with the ticket access and the departure location but often complained with the Wi‑Fi. Deutsche Bahn ticket prices on this trip start at ARS 365,104
Frequently asked questions about travelling from Brussels to Prague by train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the train ticket from Brussels to Prague?
The cheapest train tickets from Brussels to Prague start at ARS 180,781. The average price for this train route is around ARS 296,085. Busbud recommends booking your tickets in advance to increase your chances of getting the lowest possible price.
How long is the train ride from Brussels to Prague?
The average train trip from Brussels to Prague takes 15h 29m and covers 720 km. The quickest train gets you there in 12h 47m and is operated by Deutsche Bahn.
Which train operators serve the Brussels to Prague route?
Several major train operators serve this route, with 1 trains available per day.
What are the earliest and latest departure times for the train from Brussels to Prague?
The earliest train from Brussels to Prague departs at 6:06pm. The latest train departs at 7:22pm.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Brussels to Prague was searched and found on Aug 5, 2026 with a price of ARS 325,954To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Brussels to Prague, as early as possible.
You can expect to pay from ARS 325,954 to ARS 1,720,341 for a train ticket from Brussels to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at ARS 326,751 which is on 2026-08-10.
